LYNX1 is a member of the Ly-6/neurotoxin protein family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Functional analysis indicates that this protein is not a ligand or neurotransmitter but has the capacity to enhance nicotinic acetylcholine receptor function in the presence of acetylcholine. LYNX1 may also play a role in the pathogenesis of psoriasis vulgaris (1).
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