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Home All anti-LAX1 antibodies
Anti-LAX1 Antibody EP8753
Also for LAX1 (NM_001136190)
Homo sapiens lymphocyte transmembrane adaptor 1 (LAX1), transcript variant 2
A synthetic peptide corresponding to residues in the extracellular domain of human LAX1 was used as an immunogen.
Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
WB: 1:10,000 - 50,000; ICC: 1:250 - 500;
LAX1 is a single-pass type III membrane protein that negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. It is up-regulated in T-cells following TCR engagement (1).
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Western blot analysis on (A) Raji, (B) Jurkat, (C) THP-1, (D) Daudi, (E) HuT-78, and (F) HeLa cell lysates using anti-LAX1 RabMAb.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-LAX1 RabMAb.