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Anti-LASS1 Antibody EPR5816(2)
Also for LASS1 (NM_021267)
|A synthetic peptide corresponding to residues in human LASS1 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens ceramide synthase 1 (CERS1), transcript variant 1|
|LAG1; LASS1; UOG1|
Entrez Gene 10715 Human
|LASS1 is part of a group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Studies in yeast suggest that LASS1 is involved in aging (1). LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells, it is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (2). |
|Druggable Genome |
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Western blot - Anti-LASS1 antibody [EPR5816(2)]; Anti-Ceramide synthase 1 antibody [EPR5816(2)] at 1/1000 dilution + Human fetal brain lysate at 10 ug.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution
Other-Anti-Ceramide synthase 1 antibody [EPR5816(2)](TA310653); Equilibrium disassociation constant (KD)..