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Home Antibody All anti-KLK2 antibodies

Anti-KLK2 Antibody EPR6676


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against KLK2
100ul $325 3-7 Days

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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human KLK2 was used as an immunogen.
Clone NameEPR6676 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:50 - 1:100
Predicted MW Explanation 29 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens kallikrein-related peptidase 2 (KLK2), transcript variant 2
Alternative NamehGK-1; hK2; KLK2A2
Database LinkNP_001002231
Entrez Gene 3817 Human
FunctionKLK2 is a serine protease produced by secretory epithelial cells in the prostate (1). It is a glandular kallikrein that cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin (2). KLK2 can activate the proforms of PSA (prostate-specific antigen) and urokinase type plasminogen activator and inactivate plasminogen activator inhibitor-1, suggesting a possible role in a proteolytic cascade associated with prostate cancer. Thus, it may promote tumor growth, and metastasis and inhibition of KLK2 activity may, therefore, slow down tumor spread (1).
Related PathwayProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Kallikrein 2 antibody [EPR6676]; All lanes : Anti-Kallikrein 2 antibody [EPR6676] at 1/1000 dilution.Lane 1 : LnCaP lysate.Lane 2 : MOLT4 lysate.Lane 3 : Human seminoma lysate.Lane 4 : PC3 lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 29 kDa.
Other-Anti-Kallikrein 2 antibody [EPR6676](TA310646); Equilibrium disassociation constant (KD)..


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