Anti-KIFAP3 Antibody, EPR5599

Also for KIFAP3 (NM_001204514)

Gene Name	Homo sapiens kinesin-associated protein 3 (KIFAP3), transcript variant 2
Synonyms:	dJ190I16.1; FLA3; KAP-1; KAP-3; KAP3; SMAP; Smg-GDS
Immunogen	A synthetic peptide corresponding to residues at the N-terminus of human KIFAP3 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR5599	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:50 - 100;
Background	KIFAP3 contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that KIFAP3 serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein (1).
Related Pathway

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WB Image

Western blot analysis on (A) HeLa, (B) SH-SY5Y, (C) C6, (D) 293T, and (E) fetal kidney lysates using anti-KIFAP3 RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded bladder carcinoma tissue using anti-KIFAP3 RabMAb.

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Anti-KIFAP3 Antibody EPR5599

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