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Anti-ITPR1 Antibody EPR4536
Also for ITPR1 (NM_001099952)
|A synthetic peptide corresponding to residues in human ITPR1 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for IP.
|Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1|
|ACV; CLA4; INSP3R1; IP3R; IP3R1; PPP1R94; SCA15; SCA16; SCA29|
Entrez Gene 3708 Human
|ITPR1 is an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders.|
Signaling by GPCR
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Western blot - Anti-ITPR1 antibody [EPR4536]; All lanes : Anti-IP3 receptor antibody [EPR4536] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HuT78 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 314 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ITPR1 antibody [EPR4536]; TA310635, at 1/50, staining ITPR1 in paraffin-embedded Human brain tissue by immunohistochemistry.