Home All anti-INHBB antibodies
Anti-INHBB Antibody EPR2788(2)
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Also for INHBB (NM_002193)
|A synthetic peptide corresponding to residues in human Inhibin beta B was used as an immunogen.|
|Human, Mouse, Rat
||WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens inhibin, beta B (INHBB)|
|The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the inhibin beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion (1).|
Cytokine-cytokine receptor interaction
TGF Beta Signaling Pathway
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Western blot analysis on (A) mouse brain and (B) rat brain lysates using anti-Inhibin beta B RabMAb.
Western blot analysis on 10 ng of human Inhibin beta B recombinant protein (mature form: 17 kDa) using anti-Inhibin beta B RabMAb.