Anti-INHBB Antibody, EPR2788(2)

Also for INHBB (NM_002193)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in human Inhibin beta B was used as an immunogen.
Clone Name	EPR2788(2)	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens inhibin, beta B (INHBB)
Alternative Name	MGC157939
Database Link	NP_002184
Function	The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the inhibin beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion (1).
Related Pathway	Cytokine-cytokine receptor interaction TGF Beta Signaling Pathway

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WB Image

Western blot analysis on (A) mouse brain and (B) rat brain lysates using anti-Inhibin beta B RabMAb.

WB Image

Western blot analysis on 10 ng of human Inhibin beta B recombinant protein (mature form: 17 kDa) using anti-Inhibin beta B RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
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PE
FITC
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DyLight® 594
DyLight® 633

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Anti-INHBB Antibody EPR2788(2)

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data