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Anti-ING2 Antibody EPR4597


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against ING2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419856) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA recombinant protein fragment corresponding to residues in human ING2 was used as an immunogen.
Clone NameEPR4597 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:1000 - 1:2000; ICC: 1:100 - 1:250
Predicted MW Explanation 33 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens inhibitor of growth family, member 2 (ING2), transcript variant 1
Alternative NameING1L; p33ING2
Database LinkNP_001555
Entrez Gene 3622 Human
Entrez Gene 69260 Mouse
Entrez Gene 290744 Rat
FunctionING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis (1). ING2 is involved in p53/TP53 activation, by enhancing acetylation of p53/TP53. ING2 is a component of a mSin3A-like corepressor complex, which is involved in deacetylation of nucleosomal histones (2).
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ING2 antibody [EPR4597]; All lanes : Anti-ING2 antibody [EPR4597] at 1/10000 dilution.Lane 1 : T47-D cell lysate.Lane 2 : HepG2 cell lysate .Lane 3 : HT-1080 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 33 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ING2 antibody [EPR4597]; Immunohistochemical analysis of ING2 expression in formalin-fixed, paraffin-embedded Human kidney tissue using TA310630 at 1/1000 dilution.


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