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Anti-IL7 Antibody EPR6266
|A synthetic peptide corresponding to residues on the C-terminus in human IL-7 was used as an immunogen.|
|Recombinant Fragment (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens interleukin 7 (IL7), transcript variant 1|
|IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that IL-7 plays an essential role in lymphoid cell survival (1).|
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway
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Western blot - Anti-IL7 antibody [EPR6266]; Anti-IL7 antibody [EPR6266] at 1/10000 dilution + recombinant Human IL7 protein at 0.005 ug.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 20 kDa.
Other-Anti-IL7 antibody [EPR6266](TA310627); Equilibrium disassociation constant (KD)..