Anti-IL1RN Antibody, EPR6483

Also for IL1RN (NM_000577)

Gene Name	Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 3
Synonyms:	DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
Immunogen	A synthetic peptide corresponding to residues on the C-terminus in human IL-1RA was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR6483	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IP: 1:10 - 100; FC: 1:10 - 100;
Background	IL-1RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A mutation of IL-1RA is reported to be associated with increased risk of osteoporotic fractures and gastric cancer (1).
Related Pathway

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WB Image

Western blot analysis on (A) A431, (B) 293T, (C) Molt-4, (D) HeLa, (E) RAW 264.7, (F) NIH/3T3, and (G) L6 cell lysates using anti-IL-1RA RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IL-1RA RabMAb.

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Anti-IL1RN Antibody EPR6483

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