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Home Antibody All anti-IL17RA antibodies

Anti-IL17RA Antibody EPR1544(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310619
  • Rabbit Monoclonal antibody against IL-17R alpha (IL17RA)
100ul 325 3-7 Days
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WB(1)
FC(1)
Assay(1)
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Also for IL17RA (NM_014339)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-17R alpha was used as an immunogen.
Clone NameEPR1544(2) IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
BufferDoes not react with Rat. Is unsuitable for ICC/IF or IHC-P.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens interleukin 17 receptor A (IL17RA), transcript variant 1
Alternative NameCANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
Database LinkNP_055154
Entrez Gene 23765 Human
Entrez Gene 16172 Mouse
FunctionInterleukin-17R alpha is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R alpha is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure (1).
Related Pathway
Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-IL17A Receptor antibody [EPR1544(2)]; All lanes : Anti-IL17A Receptor antibody [EPR1544(2)] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Raji cell lysate.Lane 3 : RAW264.7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-rabbit at 1/2000 dilution.Predicted band size : 96 kDa.Observed band size : 125-158 kDa .
Assay Image
Other-Anti-IL17A Receptor antibody [EPR1544(2)](TA310619); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-IL17A Receptor antibody [EPR1544(2)]; Flow cytometric analysis of permeabilized HeLa cells labelling IL17A Receptor (red) with TA310619 at 1/10 and a rabbit IgG negative (green).

 

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