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Anti-IL12B Antibody EPR5738
Also for IL12B (NM_002187)
|A synthetic peptide corresponding to residues in human IL-12 beta was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:50000 - 1:200000
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens interleukin 12B (IL12B)|
|CLMF; CLMF2; IL-12B; IMD28; IMD29; NKSF; NKSF2|
Entrez Gene 3593 Human
|IL-12 beta is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Overexpression of this protein was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL-12 has been reported to be associated with the severity of atopic and non-atopic asthma in children (1). |
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Toll-like receptor signaling pathway
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Western blot - Anti-IL12 p40 antibody [EPR5738]; Anti-IL12 p40 antibody [EPR5738] at 1/50000 dilution + Human IL12 p40 recombinant protein at 0.01 ug.Predicted band size : 37 kDa.
Other-Anti-IL12 p40 antibody [EPR5738](TA310617); Equilibrium disassociation constant (KD)..