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Home Antibody All anti-IL11RA antibodies

Anti-IL11RA Antibody EPR5446

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310615 Rabbit Monoclonal antibody against IL-11R alpha (IL11RA) 100ul $325 In Stock
LC428277 IL11RA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
FC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-11R alpha was used as an immunogen.
Clone NameEPR5446 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay, IHC, FC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:500 - 1:1000; FC: 1:100 - 1:1000; ICC/IF: 1:250 - 1:500
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens interleukin 11 receptor, alpha (IL11RA), transcript variant 3
Alternative NameCRSDA
Database LinkNP_001136256
Entrez Gene 3590 Human
FunctionInterleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL-11R alpha is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain (1).
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-IL11RA antibody [EPR5446]; All lanes : Anti-IL11RA antibody [EPR5446] at 1/1000 dilution.Lane 1 : 293T lysate.Lane 2 : Saos2 lysate.Lane 3 : A673 lysate.Lane 4 : PC3 lysate.Lane 5 : Hut78 lysate.Lane 6 : K562 lysate.Lane 7 : TF1 lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 45 kDa.Observed band size : 45 kDa.
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Other-Anti-IL11RA antibody [EPR5446](TA310615); Equilibrium disassociation constant (KD)..
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL11RA antibody [EPR5446]; TA310615 at 1/500 staining IL11RA in paraffin embedded Human Kidney tissue by immunohistochemistry.
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Flow Cytometry - Anti-IL11RA antibody; Overlay histogram showing K562 cells stained with TA310615 (red line). The secondary antibody used was Alexa Fluor 488 goat anti-rabbit IgG (H&L) at 1:2000. Isotype control antibody (black line) was rabbit IgG (monoclonal) used under the same conditions. Unlabelled sample (blue line) was also used as a control. This antibody gave a positive signal in K562 cells under the same conditions.
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