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Home Antibody All anti-HTR2C antibodies

Anti-HTR2C Antibody EPR6486

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310599
  • Rabbit Monoclonal antibody against HTR2C
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424472) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HTR2C was used as an immunogen.
Clone NameEPR6486 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C), transcript variant 2
Alternative Name5-HT2C; 5-HTR2C; 5HTR2C; HTR1C
Database LinkNP_000859
FunctionSerotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. HTR2C is the 2C subtype of serotonin receptor. Its isoforms differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in HTR2C in depressed suicide victims (1).
Related Pathway
Signaling by GPCR

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-5HT2C Receptor antibody [EPR6486]; All lanes : Anti-5HT2C Receptor antibody [EPR6486] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : A431 cell lysate.Lane 3 : BxPC-3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 52 kDa.
Assay Image
Other-Anti-5HT2C Receptor antibody [EPR6486](TA310599); Equilibrium disassociation constant (KD)..

 

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