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Anti-HTR2C Antibody EPR6486
Also for HTR2C (NM_000868)
|A synthetic peptide corresponding to residues in human HTR2C was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C), transcript variant 2|
|5-HT2C; 5-HTR2C; HTR1C|
|Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. HTR2C is the 2C subtype of serotonin receptor. Its isoforms differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in HTR2C in depressed suicide victims (1).|
Signaling by GPCR
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Western blot - Anti-5HT2C Receptor antibody [EPR6486]; All lanes : Anti-5HT2C Receptor antibody [EPR6486] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : A431 cell lysate.Lane 3 : BxPC-3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 52 kDa.
Other-Anti-5HT2C Receptor antibody [EPR6486](ab124951); Equilibrium disassociation constant (KD)..