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Home Antibody All anti-HNF1B antibodies

Anti-HNF1B Antibody EPR6334(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310586
  • Rabbit Monoclonal antibody against HNF 1 Beta (HNF1B)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400162) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for HNF1B (NM_000458)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HNF 1 Beta was used as an immunogen.
Clone NameEPR6334(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens HNF1 homeobox B (HNF1B), transcript variant 1
Alternative NameFJHN; HNF-1B; HNF1beta; HNF2; HPC11; LF-B3; LFB3; MODY5; TCF-2; TCF2; VHNF1
Database LinkNP_000449
Entrez Gene 6928 Human
Entrez Gene 21410 Mouse
Entrez Gene 25640 Rat
FunctionHNF 1 Beta is a member of the homeodomain-containing superfamily of transcription factors. It binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. It has been shown to function in nephron development, and it regulates development of the embryonic pancreas. Mutations in HNF 1 Beta result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of HNF 1 Beta is altered in some types of cancer (1).
Related PathwayES Cell Differentiation/IPSEmbryonic stem cellsTranscription FactorsDruggable Genome Maturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-TCF2 antibody [EPR6334(2)]; All lanes : Anti-HNF1 beta antibody [EPR6334(2)] at 1/1000 dilution.Lane 1 : Human fetal kidney lysate.Lane 2 : Caco 2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 61 kDa.

 

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