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Home Antibody All anti-HMGA1 antibodies

Anti-HMGA1 Antibody EPR7839

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310582
  • Rabbit Monoclonal antibody against HMGA1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419517) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for HMGA1 (NM_002131)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HMGA1 was used as an immunogen.
Clone NameEPR7839 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500; ICC/IF: 1:250 - 1:500
Predicted MW Explanation 12 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2
Alternative NameHMG-R; HMGA1A; HMGIY
Database LinkNP_002122
Entrez Gene 3159 Human
Entrez Gene 15361 Mouse
Entrez Gene 117062 Rat
FunctionHMGA1 is a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. It preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. HMGA1 has little secondary structure in solution, but it assumes distinct conformations when bound to substrates such as DNA or other proteins. It is frequently acetylated and is found in the nucleus (1).
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HMGA1 antibody [EPR7839]; All lanes : Anti-HMGA1 antibody [EPR7839] at 1/10000 dilution.Lane 1 : SK-OV-3 cell lysate.Lane 2 : Caco-2 cell lysate.Lane 3 : BxPC-3 cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 12 kDa.Observed band size : 17 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMGA1 antibody [EPR7839]; TA310582, at 1/250 dilution, staining HMGA1 in paraffin-embedded Human testis tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-HMGA1 antibody [EPR7839]; TA310582, at 1/250 dilution, staining HMGA1 in BxPC-3 cells by Immunofluorescence.

 

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