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Anti-HMGA1 Antibody EPR7839

WB(1)

IHC(1)

IF(1)

Gene Name Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2 Synonyms: HMG-R; HMGA1A; HMGIY Immunogen A synthetic peptide corresponding to residues in human HMGA1 was used as an immunogen. Buffer Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. Clone Name EPR7839 Isotype Species Reactivity Human, Mouse, Rat Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IHC, IF Suggested Dilutions WB: 1:10,000 - 50,000; FC: 1:10 - 100; Background HMGA1 is a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. It preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. HMGA1 has little secondary structure in solution, but it assumes distinct conformations when bound to substrates such as DNA or other proteins. It is frequently acetylated and is found in the nucleus (1). Related Pathway Adipogenesis

Related Lysate from OriGene • Transient overexpression lysate of high mobility group AT-hook 1 (HMGA1), transcript variant 2 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • HMGA1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • HMGA1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Hmga1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • HMGA1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Hmga1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)