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Home Antibody All anti-HINT1 antibodies

Anti-HINT1 Antibody EPR5108

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310574
  • Rabbit Monoclonal antibody against Hint1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417372) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for HINT1 (NM_005340)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Hint1 was used as an immunogen.
Clone NameEPR5108 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250; FC: 1:100 - 1:500
Predicted MW Explanation 14 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens histidine triad nucleotide binding protein 1 (HINT1), transcript variant 1
Alternative NameHINT; NMAN; PKCI-1; PRKCNH1
Database LinkNP_005331
Entrez Gene 3094 Human
Entrez Gene 15254 Mouse
Entrez Gene 690660 Rat
FunctionHint1, or histidine triad nucleotide-binding protein 1, belongs to the first branch of the HIT superfamily (1). It hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Hint1 also inhibits the activity of the transcription factors AP1, MITF and USF2, as well as influences the transcription process of the Wnt/beta-catenin pathway (2). In addition, mammalian Hint1 has been suggested to have some tumor suppressor activity (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HINT1 antibody [EPR5108]; All lanes : Anti-HINT1 antibody [EPR5108] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 14 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HINT1 antibody [EPR5108]; TA310574, at 1/250 dilution, staining HINT1 in paraffin embedded breast carcinoma tissue by immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HINT1 antibody [EPR5108]; TA310574, at 1/250 dilution, staining HINT1 in paraffin embedded colonic adenocarcinoma tissue by immunohistochemistry.

 

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