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Home Antibody All anti-HINT1 antibodies

Anti-HINT1 Antibody EPR5108

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310574
  • Rabbit Monoclonal antibody against Hint1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417372) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(2)
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Also for HINT1 (NM_005340)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Hint1 was used as an immunogen.
Clone NameEPR5108 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250; FC: 1:100 - 1:500
Predicted MW Explanation 14 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens histidine triad nucleotide binding protein 1 (HINT1), transcript variant 1
Alternative NameHINT; NMAN; PKCI-1; PRKCNH1
Database LinkNP_005331
Entrez Gene 3094 Human
Entrez Gene 15254 Mouse
Entrez Gene 690660 Rat
FunctionHint1, or histidine triad nucleotide-binding protein 1, belongs to the first branch of the HIT superfamily (1). It hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Hint1 also inhibits the activity of the transcription factors AP1, MITF and USF2, as well as influences the transcription process of the Wnt/beta-catenin pathway (2). In addition, mammalian Hint1 has been suggested to have some tumor suppressor activity (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-HINT1 antibody [EPR5108]; All lanes : Anti-HINT1 antibody [EPR5108] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 14 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HINT1 antibody [EPR5108]; TA310574, at 1/250 dilution, staining HINT1 in paraffin embedded breast carcinoma tissue by immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HINT1 antibody [EPR5108]; TA310574, at 1/250 dilution, staining HINT1 in paraffin embedded colonic adenocarcinoma tissue by immunohistochemistry.
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