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Anti-HFE Antibody EPR6751(2)
|A synthetic peptide corresponding to residues in the intracellular domain of human HFE was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||IP: 1:10 - 1:100; WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens hemochromatosis (HFE), transcript variant 1|
|HFE1; HH; HLA-H; MVCD7; TFQTL2|
|HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that it functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in HFE.|
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Western blot - Anti-HFE antibody [EPR6751(2)]; All lanes : Anti-HFE antibody [EPR6751(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : A375 cell lysate.Lane 3 : Caco-2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 40 kDa.
Other-Anti-HFE antibody [EPR6751(2)](TA310572); Equilibrium disassociation constant (KD)..