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Anti-GSR Antibody EPR7237
|A synthetic peptide corresponding to residues in human Glutathione Reductase was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; FC: 1:100 - 1:500; ICC/IF: 1:250 - 1:500
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for IHC-P.
|Homo sapiens glutathione reductase (GSR), transcript variant 1|
Entrez Gene 2936 Human
|Glutathione Reductase is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. Glutathione Reductase is a central enzyme of cellular antioxidant defense and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in Glutathione Reductase result in hereditary glutathione reductase deficiency (1).|
|Druggable Genome Glutathione metabolism|
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Western blot - Anti-Glutathione Reductase antibody [EPR7237]; All lanes : Anti-Glutathione Reductase antibody [EPR7237] at 1/10000 dilution.Lane 1 : Caco-2 cell lysate.Lane 2 : A549 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 56 kDa.Observed band size : 50 kDa .
Immunocytochemistry/ Immunofluorescence - Anti-Glutathione Reductase antibody [EPR7237]; TA310555, at a 1/100 dilution, staining Human Glutathione Reductase in HeLa cells, by Immunofluorescence.