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Home Antibody All anti-GRIK2 antibodies

Anti-GRIK2 Antibody EPR6307

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310550
  • Rabbit Monoclonal antibody against GluR6 (GRIK2)
100ul 325 In Stock
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WB(1)
IHC(3)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human GluR6 was used as an immunogen.
Clone NameEPR6307 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IP.

Reference Data

Target NameHomo sapiens glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 3
Alternative NameEAA4; GLR6; GluK2; GLUK6; GLUR6; MRT6
Database LinkNP_001159719
Entrez Gene 2898 Human
Entrez Gene 14806 Mouse
Entrez Gene 54257 Rat
FunctionGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. GluR6 belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Mutations in GluR6 have been associated with autosomal recessive mental retardation (1).
Related PathwayTransmembraneIon Channels: Glutamate ReceptorsDruggable Genome Neuroactive ligand-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-GRIK2 antibody [EPR6307]; All lanes : Anti-GRIK2 antibody [EPR6307] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : Human kidney lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 103 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GRIK2 antibody [EPR6307]; TA310550, at 1/250 dilution, staining GRIK2 in paraffin-embedded Human brain tissue by immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GRIK2 antibody [EPR6307]; TA310550, at 1/250 dilution, staining GRIK2 in paraffin-embedded Human colon tissue by immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GRIK2 antibody [EPR6307]; TA310550, at 1/250 dilution, staining GRIK2 in paraffin-embedded Human kidney tissue by immunohistochemistry.

 

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