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Anti-GP9 Antibody EP5294
|A synthetic peptide corresponding to residues in human CD42a was used as an immunogen|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens glycoprotein IX (platelet) (GP9)|
Entrez Gene 2815 Human
|CD42a is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with CD42a and platelet glycoprotein V. Defects in CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.|
|TransmembraneDruggable Genome ECM-receptor interactionHematopoietic cell lineage|
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Western blot - Anti-CD42a antibody [EP5294]; All lanes : Anti-CD42a antibody [EP5294] at 1/10000 dilution.Lane 1 : Human platelet lysate.Lane 2 : PBMC lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 19 kDa.Observed band size : 19 kDa.
Other-Anti-CD42a antibody [EP5294](TA310544); Equilibrium disassociation constant (KD)..