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Home All anti-GAP43 antibodies
Anti-GAP43 Antibody EP928Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for GAP43 (NM_001130064)
OriGene Data
| A synthetic peptide corresponding to residues surrounding serine 41 of human GAP43 was used as an immunogen. This antibody detects both phosphorylated and nonphosphorylated GAP43. |
| EP928Y |
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| Human, Mouse, Rat |
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| WB |
WB: 1:1000; IP: 1:40; |
| Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens growth associated protein 43 (GAP43), transcript variant 1 |
| B-50; PP46 |
| NP_001123536 |
| Growth associated protein GAP43 (B-50, F1, neuromodulin) is a phosphoprotein of the presynaptic membrane involved in synaptic reorganization and neural development. Phospholyated at Ser41 by protein kinase C (PKC), phospholyated GAP43 has been correlated to release of neurotransmitters in mature nervous system (1). Also, GAP43 plays an essential role in the maintenance mechanism of long-term potentiation (LTP) (2). These suggest GAP43 to play a role in synaptic plasticity. For neurons in development or regeneration, GAP43 is a major component of the growth cone, which enables elongation and navigation of developing axons (3). During periods of low activity in neurons, Calmodulin binds to GAP43 when Ca2+ is low, suggesting Calmodulin as a negative regulator of GAP43 (4). |
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* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
A. Western blot analysis on human brain lysate using anti-GAP43 RabMAb.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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