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Home Antibody All anti-FZD6 antibodies

Anti-FZD6 Antibody EPR7279

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310509
  • Rabbit Monoclonal antibody against Frizzled-6 (FZD6)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC432028) , 20ug
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for FZD6 (NM_001164615)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Frizzled-6 was used as an immunogen.
Clone NameEPR7279 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens frizzled class receptor 6 (FZD6), transcript variant 2
Alternative NameFZ-6; FZ6; HFZ6; NDNC10
Database LinkNP_001158087
FunctionFrizzled-6 represents a member of the 'frizzled' family, which are 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Frizzled-6 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. It functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis (1).
Related Pathway
Melanogenesis
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Frizzled 6 antibody [EPR7279]; All lanes : Anti-Frizzled 6 antibody [EPR7279] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HT 29 cell lysate.Lane 3 : 293T cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 79 kDa.
Assay Image
Other-Anti-Frizzled 6 antibody [EPR7279](TA310509); Equilibrium disassociation constant (KD)..

 

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