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Anti-FXN Antibody EPR6107


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310506 Rabbit Monoclonal antibody against Frataxin (FXN) 100ul $325 In Stock
LC400054 FXN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Frataxin was used as an immunogen.
Clone NameEPR6107 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay Suggested DilutionsWB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens frataxin (FXN), transcript variant 1
Alternative NameCyaY; FA; FARR; FRDA; X25
Database LinkNP_000135
Entrez Gene 2395 Human
FunctionFrataxin is a mitochondrial protein that belongs to the FRATAXIN family. It functions in regulating mitochondrial iron transport and respiration (1). Frataxin is crucial for iron–sulfur cluster (ISC) biosynthesis and plays a primary role in their protein maturation in human cells (2). A reduced level of functional protein results in Friedreich ataxia (1, 2).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Frataxin antibody [EPR6107]; All lanes : Anti-Frataxin antibody [EPR6107] at 1/1000 dilution.Lane 1 : Human heart lysate.Lane 2 : Human fetal skin lysate.Lane 3 : PBL lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 19, 23 kDa.Observed band size : 17,30 kDa .

Assay Image
Other-Anti-Frataxin antibody [EPR6107](TA310506); Equilibrium disassociation constant (KD)..


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