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Home Antibody All anti-FUS antibodies

Anti-FUS Antibody EPR5812

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310505 Rabbit Monoclonal antibody against FUS 100ul $325 In Stock
LC401541 FUS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FUS was used as an immunogen.
Clone NameEPR5812 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
Predicted MW Explanation 53 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens fusion (involved in t(12;16) in malignant liposarcoma) (FUS), transcript variant 2
Alternative NameTLS, FUS1, FUS-CHOP
Database LinkNP_001010850
Entrez Gene 2521 Human
Entrez Gene 233908 Mouse
Entrez Gene 317385 Rat
FunctionFUS is a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. FUS belongs to the FET family of RNA-binding proteins, which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Defects in FUS result in amyotrophic lateral sclerosis type 6 (1).
Related PathwayStem cell - PluripotencyDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-TLS/FUS antibody [EPR5812]; All lanes : Anti-TLS/FUS antibody [EPR5812] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : Human fetal brain lysate.Lane 3 : Caco 2 cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 73 kDa .
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Other-Anti-TLS/FUS antibody [EPR5812](TA310505); Equilibrium disassociation constant (KD)..
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TLS/FUS antibody [EPR5812]; TA310505, at 1/50 dilution, staining TLS/FUS in formalin-fixed, paraffin-embedded Human kidney tissue, by Immunohistochemistry.
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