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Anti-Fos Antibody EPR883(2)
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|A synthetic peptide corresponding to residues in human Fos was used as an immunogen.|
|Human, Mouse, Rat
||WB: 1:1,000-10,000; IHC 1:250 - 500; ICC: 1:100 - 250; IP: 1:10 - 100; FC: 1:10 - 100;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens FBJ murine osteosarcoma viral oncogene homolog (FOS)|
|AP-1; C-FOS; p55|
|Fos is nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, Fos and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (1). In some cases, expression of the FOS protein has also been associated with apoptotic cell death (2).|
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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Western blot analysis on (A) U937 treated with TPA, (B) U937, (C) HeLa treated with TPA, and (D) HeLa cell lysates using anti-Fos RabMAb.