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Home All anti-Fos antibodies

Anti-Fos Antibody EPR883(2)

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310495
  • Rabbit Monoclonal antibody against Fos
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401614) , 20ug
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Fos was used as an immunogen.
Clone NameEPR883(2) Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000-10,000; IHC 1:250 - 500; ICC: 1:100 - 250; IP: 1:10 - 100; FC: 1:10 - 100;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens FBJ murine osteosarcoma viral oncogene homolog (FOS)
Alternative NameAP-1; C-FOS; p55
Database LinkNP_005243
FunctionFos is nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, Fos and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (1). In some cases, expression of the FOS protein has also been associated with apoptotic cell death (2).
Related Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis on (A) U937 treated with TPA, (B) U937, (C) HeLa treated with TPA, and (D) HeLa cell lysates using anti-Fos RabMAb.

 

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