Anti-FLAP Antibody, EPR5640

Also for FLAP (NM_001629)

Gene Name	Homo sapiens arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1
Synonyms:	FLAP
Immunogen	A synthetic peptide corresponding to residues in human FLAP was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR5640	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; ICC: 1:100 - 250;
Background	FLAP, along with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites that have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. It localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation (1).
Related Pathway

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WB Image

Western blot analysis on (A) Raji, (B) THP-1, (C) HepG2, and (D) K562 cell lysates using anti-FLAP RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
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PE
FITC
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DyLight® 594
DyLight® 633

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OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

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Anti-FLAP Antibody EPR5640

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