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Home Antibody All anti-ALOX5AP antibodies

Anti-ALOX5AP Antibody EPR5640


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310491 Rabbit Monoclonal antibody against FLAP 100ul $325 In Stock
LC400611 ALOX5AP HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for ALOX5AP (NM_001629)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FLAP was used as an immunogen.
Clone NameEPR5640 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, Assay Suggested DilutionsWB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens arachidonate 5-lipoxygenase activating protein (ALOX5AP), transcript variant 1
Alternative NameFLAP
Database LinkNP_001620
Entrez Gene 241 Human
FunctionFLAP, along with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites that have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. It localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation (1).
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-FLAP antibody [EPR5640]; All lanes : Anti-FLAP antibody [EPR5640] at 1/1000 dilution.Lane 1 : Raji cell lysates.Lane 2 : THP1 cell lysates.Lane 3 : HepG2 cell lysates.Lane 4 : K562 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 18 kDa.

Assay Image
Other-Anti-FLAP antibody [EPR5640](TA310491); Equilibrium disassociation constant (KD)..


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