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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-FBP1 antibodies

Anti-FBP1 Antibody EPR4619

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310482
  • Rabbit Monoclonal antibody against FBP1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424655) , 20ug
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IHC(2)
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Also for FBP1 (NM_000507)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens fructose-1,6-bisphosphatase 1 (FBP1), transcript variant 1
Synonyms:FBP
ImmunogenA synthetic peptide corresponding to residues in human FBP1 was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR4619 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000-10,000; IHC 1:50 - 100; ICC: 1:250 - 500; IP: 1:10 - 100;
BackgroundFBP1 (Fructose-1,6-bisphosphatase 1) is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate (1). It is a key, rate-controlling enzyme of gluconeogenesis, an important metabolic pathway that allows the cells to synthesize glucose and grow on non-carbohydrate carbon sources, such as glycerol, organic acids and amino acids (2). Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) MCF-7, (B) fetal liver, and (C) HL-60 treated with vitamin D3 lysates using anti-FBP1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FBP1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-FBP1 RabMAb.

 

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