Anti-FAAH Antibody, EPR7549

Also for FAAH (NM_001441)

Gene Name	Homo sapiens fatty acid amide hydrolase (FAAH)
Synonyms:	FAAH-1
Immunogen	A synthetic peptide corresponding to residues in human FAAH was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7549	Isotype
Species Reactivity	Human, Mouse	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; ICC: 1:100 - 250; FC: 1:100 - 500;
Background	FAAH belongs to the amidase signature (AS) superfamily of serine hydrolases (1). It is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide (2). The most prominent substrates of FAAH are endocannabinoids, fatty acid amides that activate cannabinoid (CB) receptors. Through hydrolysis of endocannabinoids, FAAH terminates CB receptor signaling and controls the endocannabinoid tone (3).
Related Pathway

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WB Image

Western blot analysis on (A) human testis, (B) JAR, and (C) A431 lysates using anti-FAAH RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-FAAH RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FAAH RabMAb.

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Anti-FAAH Antibody EPR7549

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