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Anti-F5 Antibody EPR5191
|A synthetic peptide corresponding to residues in the light chain of human Factor V was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens coagulation factor V (proaccelerin, labile factor) (F5)|
|FVL; PCCF; RPRGL1; THPH2|
Entrez Gene 2153 Human
|Factor V is an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in Factor V result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance (1).|
|Druggable Genome Complement and coagulation cascades|
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Western blot - Factor V antibody [EPR5191]; All lanes : Anti-Factor V antibody [EPR5191] at 1/1000 dilution.Lane 1 : Human plasma lysate.Lane 2 : Human platelet lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 252 kDa.