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Home Antibody All anti-F2 antibodies

Anti-F2 Antibody EPR5188

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310472
  • Rabbit Monoclonal antibody against Prothrombin (F2)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400182) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for F2 (NM_000506)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Prothrombin was used as an immunogen.
Clone NameEPR5188 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens coagulation factor II (thrombin) (F2)
Alternative NamePT; RPRGL2; THPH1
Database LinkNP_000497
FunctionCoagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade, which ultimately results in the stemming of blood loss. Prothrombin (F2) plays a role in maintaining vascular integrity during development and postnatal life (1). It converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Prothrombin also functions in blood homeostasis, inflammation, and wound healing (2). Mutations in this protein lead to various forms of thrombosis and dysprothrombinemia (1).
Related Pathway
Hemostasis
Signaling by GPCR

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WB Image
Western blot - Prothrombin antibody [EPR5188]; All lanes : Anti-Prothrombin antibody [EPR5188] at 1/1000 dilution.Lane 1 : Human serum lysate.Lane 2 : Human plasma lysate.Lane 3 : Human platelet lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 70 kDa.

 

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