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Anti-F2 Antibody EPR5188


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against Prothrombin (F2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400182) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Prothrombin was used as an immunogen.
Clone NameEPR5188 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens coagulation factor II (thrombin) (F2)
Alternative NamePT; RPRGL2; THPH1
Database LinkNP_000497
Entrez Gene 2147 Human
FunctionCoagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade, which ultimately results in the stemming of blood loss. Prothrombin (F2) plays a role in maintaining vascular integrity during development and postnatal life (1). It converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Prothrombin also functions in blood homeostasis, inflammation, and wound healing (2). Mutations in this protein lead to various forms of thrombosis and dysprothrombinemia (1).
Related PathwaySecreted ProteinProteaseDruggable Genome Neuroactive ligand-receptor interactionComplement and coagulation cascadesRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Prothrombin antibody [EPR5188]; All lanes : Anti-Prothrombin antibody [EPR5188] at 1/1000 dilution.Lane 1 : Human serum lysate.Lane 2 : Human plasma lysate.Lane 3 : Human platelet lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 70 kDa.


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