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 Home All anti-EphB3 antibodies

Anti-EphB3 Antibody EPR8280

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310461
  • Rabbit Monoclonal antibody against EphB3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401410) , 20ug
 100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IF(1)
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Also for EphB3 (NM_004443)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human EphB3 was used as an immunogen.
Clone NameEPR8280 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1,000 - 10,000;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens EPH receptor B3 (EPHB3)
Alternative NameETK2; HEK2; TYRO6
Database LinkNP_004434
FunctionEphB3 is a receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional singnaling into neighboring cells. It plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. EphB3 controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. It also plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) Jurkat, (B) HeLa, (C) HepG2, (D) Molt-4, and (E) NIH/3T3 cell lysates using anti-EphB3 RabMAb.
IF Image
Immunofluorescent staining of HeLa cells using anti-EphB3 RabMAb.

 

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