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Anti-EDNRB Antibody EPR7013
Also for EDNRB (NM_000115)
|A synthetic peptide corresponding to residues in human Endothelin B receptor was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:100 - 1:500; ICC/IF: 1:50 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for IHC-P.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for IHC-P.
|Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1|
|ABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A|
|Endothelin B receptor is a G protein-coupled receptor that activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in endothelin receptor type B (1).|
Signaling by GPCR
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Western blot - Anti-Endothelin B Receptor antibody [EPR7013]; All lanes : Anti-Endothelin B Receptor antibody [EPR7013] at 1/1000 dilution.Lane 1 : Raji cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : JAR cell lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 50 kDa.
Other-Anti-Endothelin B Receptor antibody [EPR7013](ab129102); Equilibrium disassociation constant (KD)..
Immunocytochemistry/ Immunofluorescence - Anti-Endothelin B Receptor antibody [EPR7013]; ab129102, at 1/50 dilution, staining Endothelin B receptor in HeLa cells by Immunofluorescence.