Anti-EDNRB Antibody, EPR7013

Also for EDNRB (NM_000115)

Gene Name	Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1
Synonyms:	ABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A
Immunogen	A synthetic peptide corresponding to residues in human Endothelin B receptor was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7013	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IF	Suggested Dilutions	WB: 1:1,000 - 10,000;
Background	Endothelin B receptor is a G protein-coupled receptor that activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in endothelin receptor type B (1).
Related Pathway	Melanogenesis Signaling by GPCR

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WB Image

Western blot analysis on (A) Raji, (B) HeLa, (C) JAR, and (D) 293T cell lysates using anti-Endothelin B receptor RabMAb.

IF Image

Immunofluorescent staining of HeLa cells using anti-Endothelin B receptor RabMAb.

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Anti-EDNRB Antibody EPR7013

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