Anti-DTNBP1 Antibody, EPR7042(B)

Also for DTNBP1 (NM_032122)

Gene Name	Homo sapiens dystrobrevin binding protein 1 (DTNBP1), transcript variant 1
Synonyms:	BLOC1S8; DBND; HPS7; My031; SDY
Immunogen	A synthetic peptide corresponding to residues on the C-terminus in human Dysbindin was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7042(B)	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:10,000 - 50,000;
Background	Dysbindin is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in Dysbindin are associated with Hermansky-Pudlak syndrome type 7. It may also be associated with schizophrenia (1).
Related Pathway

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WB Image

Western blot analysis on (A) SH-SY5Y, (B) HeLa, (C) HepG2, and (D) 293T cell lysates using anti-Dysbindin RabMAb.

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Anti-DTNBP1 Antibody EPR7042(B)

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