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Anti-DPYSL3 Antibody EPR7592(B)
Also for DPYSL3 (NM_001197294)
|A synthetic peptide corresponding to residues on the N-terminus in human CRMP-4 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens dihydropyrimidinase-like 3 (DPYSL3), transcript variant 1|
|CRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1|
|CRMP-4 is a cytosolic phosphoprotein known to regulate cytoskeletal dynamics and is a known physiological substrate of GSK3. It has been shown to promote F-actin bundling. Furthermore, CRMP4, but not other CRMP family members, binds to RhoA, an important regulator of cell cycle progression and cytokinesis. These observations show that CRMP4 plays a role in regulating microtubule dynamics during mitosis (1). CRMP4 also influences neurite outgrowth (2). Thus, CRMP4 is involved in semaphorin-induced growth cone collapse and axonal guidance in developing neurons (3).|
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Western blot - Anti-CRMP4 antibody [EPR7592(B)]; All lanes : Anti-CRMP4 antibody [EPR7592(B)] at 1/1000 dilution.Lane 1 : Human hippocampus tissue lysate.Lane 2 : Human fetal brain tissue lysate.Lane 3 : SHSY-5Y cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 62 kDa.
Other-Anti-CRMP4 antibody [EPR7592(B)](ab128855); Equilibrium disassociation constant (KD)..