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Anti-DPYSL3 Antibody EPR7592(B)


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against CRMP-4 (DPYSL3)
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the N-terminus in human CRMP-4 was used as an immunogen.
Clone NameEPR7592(B) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 62 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens dihydropyrimidinase-like 3 (DPYSL3), transcript variant 1
Alternative NameCRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1
Database LinkNP_001184223
Entrez Gene 1809 Human
Entrez Gene 22240 Mouse
Entrez Gene 25418 Rat
FunctionCRMP-4 is a cytosolic phosphoprotein known to regulate cytoskeletal dynamics and is a known physiological substrate of GSK3. It has been shown to promote F-actin bundling. Furthermore, CRMP4, but not other CRMP family members, binds to RhoA, an important regulator of cell cycle progression and cytokinesis. These observations show that CRMP4 plays a role in regulating microtubule dynamics during mitosis (1). CRMP4 also influences neurite outgrowth (2). Thus, CRMP4 is involved in semaphorin-induced growth cone collapse and axonal guidance in developing neurons (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-CRMP4 antibody [EPR7592(B)]; All lanes : Anti-CRMP4 antibody [EPR7592(B)] at 1/1000 dilution.Lane 1 : Human hippocampus tissue lysate.Lane 2 : Human fetal brain tissue lysate.Lane 3 : SHSY-5Y cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 62 kDa.
Other-Anti-CRMP4 antibody [EPR7592(B)](TA310420); Equilibrium disassociation constant (KD)..


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