Anti-DPYSL2 Antibody, EPR7792

Also for DPYSL2 (NM_001197293)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near the C-terminus of human CRMP-2 was used as an immunogen.
Clone Name	EPR7792	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 1
Alternative Name	CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
Database Link	NP_001184222
Function	CRMP-2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. CRMP-2 promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This protein has been implicated in multiple neurological disorders, and hyperphosphorylation of CRMP-2 may play a key role in the development of Alzheimer's disease (1).
Related Pathway

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WB Image

Western blot analysis on (A) PC-12, (B) Jurkat, (C) U87-MG, and (D) NIH/3T3 cell lysates using anti-CRMP-2 RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human astrocytoma tissue using anti-CRMP-2 RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
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DyLight® 594
DyLight® 633

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OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-DPYSL2 Antibody EPR7792

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data