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Anti-DPYSL2 Antibody EPR7792
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Also for DPYSL2 (NM_001197293)
|A synthetic peptide corresponding to residues near the C-terminus of human CRMP-2 was used as an immunogen.|
|Human, Mouse, Rat
||WB: 1:1,000 - 10,000; IHC 1:100 - 250;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 1|
|CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2|
|CRMP-2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. CRMP-2 promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This protein has been implicated in multiple neurological disorders, and hyperphosphorylation of CRMP-2 may play a key role in the development of Alzheimer's disease (1). |
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Western blot analysis on (A) PC-12, (B) Jurkat, (C) U87-MG, and (D) NIH/3T3 cell lysates using anti-CRMP-2 RabMAb.
Immunohistochemical analysis of paraffin-embedded human astrocytoma tissue using anti-CRMP-2 RabMAb.