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Home Antibody All anti-DPYSL2 antibodies

Anti-DPYSL2 PHOSPHO Antibody EPR7876

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310418
  • Rabbit Monoclonal antibody against CRMP-2, pT514 (DPYSL2) (Phospho-specific)
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for DPYSL2 (NM_001386)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding Threonine 514 of human CRMP-2 was used as an immunogen. This antibody only detects CRMP-2 phosphorylated at Threonine 514.
Clone NameEPR7876 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2
Alternative NameCRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
Database LinkNP_001377
FunctionCRMP-2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. CRMP-2 promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This protein has been implicated in multiple neurological disorders, and hyperphosphorylation of CRMP-2 may play a key role in the development of Alzheimer's disease (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CRMP2 (phospho T514) antibody [EPR7876]; All lanes : Anti-CRMP2 (phospho T514) antibody [EPR7876] at 1/1000 dilution.Lane 1 : Human fetal brain lysate, untreated .Lane 2 : Human fetal brain lysate, treated with Lambda Phosphatase.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 62 kDa.
Assay Image
Other-Anti-CRMP2 (phospho T514) antibody [EPR7876](TA310418); Equilibrium disassociation constant (KD)..

 

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