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Anti-DPYD Antibody EPR8811
Also for DPYD (NM_000110)
|A synthetic peptide corresponding to residues in human DPYD was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC/IF: 1:250 - 1:500
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.|
|Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1|
|DHP; DHPDHASE; DPD|
|DPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this protein result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy (1). |
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Western blot - Anti-DPYD antibody [EPR8811]; All lanes : Anti-DPYD antibody [EPR8811] at 1/1000 dilution.Lane 1 : Fetal kidney cell lysate.Lane 2 : THP1 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 110 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DPYD antibody [EPR8811]; Immunohistochemical analysis of paraffin-embedded Human colon tissue staining DPYD with ab134922 at 1/250 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DPYD antibody [EPR8811]; Immunohistochemical analysis of paraffin-embedded Human lung tissue staining DPYD with ab134922 at 1/250 dilution.