Anti-DAZL Antibody, EPR5140

Also for DAZL (NM_001351)

Gene Name	Homo sapiens deleted in azoospermia-like (DAZL), transcript variant 2
Synonyms:	DAZH; DAZL1; DAZLA; SPGYLA
Immunogen	A synthetic peptide corresponding to residues in human DAZL was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR5140	Isotype
Species Reactivity	Human, Mouse	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:50,000 - 200,000;
Background	The DAZ (Deleted in AZoospermia) family are potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of DAZL during primate evolution gave rise to DAZ on the Y chromosome. Mutations in DAZL have been linked to severe spermatogenic failure and infertility in males.
Related Pathway

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WB Image

Western blot analysis on (A) human testis and (B) human small intestine lysates using anti-DAZL RabMAb.

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Anti-DAZL Antibody EPR5140

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