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Home Antibody All anti-DAPP1 antibodies

Anti-DAPP1 Antibody EPR4993(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310391
  • Rabbit Monoclonal antibody against DAPP1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402326) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
Assay(1)
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Also for DAPP1 (NM_014395)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DAPP1 was used as an immunogen.
Clone NameEPR4993(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 32 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1)
Alternative NameBAM32
Database LinkNP_055210
Entrez Gene 27071 Human
Entrez Gene 26377 Mouse
Entrez Gene 362046 Rat
FunctionDAPP1 is an SH2 and pleckstrin homology (PH) domain-containing adapter molecule expressed in B cells, T cells, dendritic cells and macrophages (1). It binds PI3K lipid products, phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate, in vitro and is recruited to the plasma membrane in a PI3K-dependent manner upon B-cell antigen receptor (BCR) ligation. DAPP1 has been implicated in BCR signaling processes, including activation of the GTPase Rac1 and MAPKs ERK and JNK (2).
Related PathwayPhosphataseDruggable Genome B cell receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-DAPP1 antibody [EPR4993(2)]; All lanes : Anti-DAPP1 antibody [EPR4993(2)] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : IM-9 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 32 kDa.
Assay Image
Other-Anti-DAPP1 antibody [EPR4993(2)](TA310391); Equilibrium disassociation constant (KD)..

 

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