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Anti-DAPP1 Antibody EPR4993(2)
Also for DAPP1 (NM_014395)
|A synthetic peptide corresponding to residues in human DAPP1 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC,ICC/IF,IHC-P or IP.
|Homo sapiens dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1)|
|DAPP1 is an SH2 and pleckstrin homology (PH) domain-containing adapter molecule expressed in B cells, T cells, dendritic cells and macrophages (1). It binds PI3K lipid products, phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate, in vitro and is recruited to the plasma membrane in a PI3K-dependent manner upon B-cell antigen receptor (BCR) ligation. DAPP1 has been implicated in BCR signaling processes, including activation of the GTPase Rac1 and MAPKs ERK and JNK (2). |
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Western blot - Anti-DAPP1 antibody [EPR4993(2)]; All lanes : Anti-DAPP1 antibody [EPR4993(2)] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : IM-9 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 32 kDa.
Other-Anti-DAPP1 antibody [EPR4993(2)](TA310391); Equilibrium disassociation constant (KD)..