OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
Home All anti-CYP27A1 antibodies
Anti-CYP27A1 Antibody EPR7529
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
Also for CYP27A1 (NM_000784)
Homo sapiens cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), nuclear gene encoding mitochondrial protein CP27; CTX; CYP27 A synthetic peptide corresponding to residues in human CYP27A1 was used as an immunogen. Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
EPR7529
Human, Mouse, Rat
(Protein A or G Sepharose )
WB, IHC, IF
WB: 1:1,000 - 10,000;
CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, CYP27A1 is important for overall cholesterol homeostasis. Mutations in CYP27A1 cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease (1).
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WB Image
Western blot analysis on (A) HepG2, (B) Caco-2, (C) fetal liver, and (D) mouse liver lysates using anti-CYP27A1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CYP27A1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CYP27A1 RabMAb.
IF Image
Western blot analysis on (A) HepG2, (B) Caco-2, (C) fetal liver, and (D) mouse liver lysates using anti-CYP27A1 RabMAb.
IF Image
Immunofluorescent staining of HepG2 cells using anti-CYP27A1 RabMAb.
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