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Home Antibody All anti-CXCL1 antibodies

Anti-CXCL1 Antibody EPR4902

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310382
  • Rabbit Monoclonal antibody against GRO alpha (CXCL1)
100ul $325 3-7 Days
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WB(1)
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Also for CXCL1 (NM_001511)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GRO alpha was used as an immunogen.
Clone NameEPR4902 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC/IF,IHC-P or IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1), transcript variant 1
Alternative NameFSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1
Database LinkNP_001502
FunctionChemokines are a group of small (approximately 8 to 14 kDa), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines such as GRO alpha are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes (1).
Related Pathway
Cytokine-cytokine receptor interaction
Senescence and Autophagy
Signaling by GPCR

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WB Image
Western blot - Anti-GRO alpha antibody [EPR4902]; Anti-GRO alpha antibody [EPR4902] at 1/10000 dilution + Human GRO alpha recombinant protein at 0.01 µg.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 11 kDa.

 

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