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Anti-COMT Antibody EPR6491(B)
Also for COMT (NM_000754)
|A synthetic peptide corresponding to residues in human COMT was used as an immunogen.|
||Tissue culture supernatant
|Rat, Human (Does not react with: Mouse)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens catechol-O-methyltransferase (COMT), transcript variant 1|
Entrez Gene 1312 Human
Entrez Gene 24267 Rat
|Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson's disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini (1). |
|TransmembraneDruggable Genome Tyrosine metabolismMetabolic pathways|
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Western blot - Anti-COMT antibody [EPR6491(B)]; All lanes : Anti-COMT antibody [EPR6491(B)] at 1/1000 dilution.Lane 1 : Fetal Liver lysate .Lane 2 : A431 cell lysate .Lane 3 : MOLT4 cell lysate.Lysates/proteins at 10 ug per lane.developed using the ECL technique.Predicted band size : 30 kDa.
Other-Anti-COMT antibody [EPR6491(B)](TA310342); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-COMT antibody [EPR6491(B)]; TA310342, at 1/10 dilution staining COMT in A431 cells, (Red) compared to a nonspecific negative control antibody (Green) by Flow Cytometry.