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Anti-CD30 Antibody EPR4102

Gene Name Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 Synonyms: CD30; D1S166E; Ki-1 Immunogen A synthetic peptide corresponding to residues at the C-terminus of human CD30 was used as an immunogen. Buffer Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. Clone Name EPR4102 Isotype Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * Suggested Dilutions WB: 1:10,000 - 50,000; IHC 1:500-1000; Background CD30, TNF-receptor superfamily member, is a receptor for TNFSF8/CD30L. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity (1). Related Pathway Cytokine-cytokine receptor interaction

Related Lysate from OriGene • Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • TNFRSF8 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • TNFRSF8 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Tnfrsf8 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • TNFRSF8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Tnfrsf8 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 as transfection-ready DNA Related cDNA Clones • Homo sapiens tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)