OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-CD27 antibodies

Anti-CD27 Antibody EPR8568

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310268
  • Rabbit Monoclonal antibody against CD27
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400496) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(1)
IF(1)
Assay(1)
spacer
Also for CD27 (NM_001242)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human CD27 was used as an immunogen.
Clone NameEPR8568 IsotypeTissue culture supernatant
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
BufferDoes not react with Mouse. Is unsuitable for IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens CD27 molecule (CD27)
Alternative NameS152; S152. LPFS2; T14; TNFRSF7; Tp55
Database LinkNP_001233
FunctionCD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor (1).
Related Pathway
Cytokine-cytokine receptor interaction

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CD27 antibody [EPR8568]; Anti-CD27 antibody [EPR8568] at 1/1000 dilution + Ramos cell lysate at 10 µg.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 29 kDa.
Assay Image
Other-Anti-CD27 antibody [EPR8568](TA310268); Equilibrium disassociation constant (KD)..
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-CD27 antibody [EPR8568]; Immunofluorescent staining of CD27 in Ramos cells, using TA310268 at a 1/50 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title