Anti-CD27 Antibody, EPR8568

Also for CD27 (NM_001242)

Gene Name	Homo sapiens CD27 molecule (CD27)
Synonyms:	S152; T14; TNFRSF7; Tp55
Immunogen	A synthetic peptide corresponding to residues in the extracellular domain of human CD27 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR8568	Isotype
Species Reactivity	Human, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IF	Suggested Dilutions	WB: 1:1,000 - 10,000; FC: 1:10 - 100;
Background	CD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor (1).
Related Pathway	Cytokine-cytokine receptor interaction

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

Western blot analysis on Ramos cell lysate using anti-CD27 RabMAb.

IF Image

Immunofluorescent staining of Ramos cells using anti-CD27 RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

OriGene Antibodies in recent publications

Anti-CD27 Antibody EPR8568

TrueMAB™ Antibodies - Made against Authentic Protein Antigens