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Anti-CD27 Antibody EPR8569
Also for CD27 (NM_001242)
|A synthetic peptide corresponding to residues in the intracellular domain of human CD27 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500; FC: 1:100 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IP.
|Homo sapiens CD27 molecule (CD27)|
|S152; S152. LPFS2; T14; TNFRSF7; Tp55|
|CD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor (1).|
Cytokine-cytokine receptor interaction
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Western blot - Anti-CD27 antibody [EPR8569]; All lanes : Anti-CD27 antibody [EPR8569] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : Human lymph node cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti Rabbit IgG at 1/2000 dilution.Predicted band size : 29 kDa.
Other-Anti-CD27 antibody [EPR8569](TA310267); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD27 antibody [EPR8569]; Immunohistochemical analysis of paraffin embedded Human stomach tissue labelling CD27 with TA310267 antibody at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD27 antibody [EPR8569]; Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelling CD27 with TA310267 antibody at 1/100 dilution.