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Home Antibody All anti-CD27 antibodies

Anti-CD27 Antibody EPR8569

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SKU Description Amount Price Availability*  
TA310267
  • Rabbit Monoclonal antibody against CD27
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400496) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(2)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the intracellular domain of human CD27 was used as an immunogen.
Clone NameEPR8569 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500; FC: 1:100 - 1:500
Predicted MW Explanation 29 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens CD27 molecule (CD27)
Alternative NameS152; S152. LPFS2; T14; TNFRSF7; Tp55
Database LinkNP_001233
Entrez Gene 939 Human
Entrez Gene 21940 Mouse
Entrez Gene 500318 Rat
FunctionCD27 is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor (1).
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-CD27 antibody [EPR8569]; All lanes : Anti-CD27 antibody [EPR8569] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : Human lymph node cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti Rabbit IgG at 1/2000 dilution.Predicted band size : 29 kDa.
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Other-Anti-CD27 antibody [EPR8569](TA310267); Equilibrium disassociation constant (KD)..
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD27 antibody [EPR8569]; Immunohistochemical analysis of paraffin embedded Human stomach tissue labelling CD27 with TA310267 antibody at 1/100 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD27 antibody [EPR8569]; Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelling CD27 with TA310267 antibody at 1/100 dilution.
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