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Home Antibody All anti-CD23 antibodies

Anti-CD23 Antibody EPR3617

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310263
  • Rabbit Monoclonal antibody against CD23
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419592) , 20ug
100ul 325 3-7 Days
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WB(2)
IHC(5)
Assay(1)
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Also for CD23 (NM_002002)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD23 was used as an immunogen.
Clone NameEPR3617 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:2500 - 5000; IP: 1:50;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1
Alternative NameBLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF
Database LinkNP_001993
FunctionCD23, a type II transmembrane glycoprotein, is a key molecule for B-cell activation and growth and functions as a receptor for IgE. It plays essential roles in the regulation of IgE production and in the differentiation of B-cells. CD21 has been identified as a ligand for CD23 in the control of IgE production. It is expressed in many hematopoietic cell types (1). CD23 expression is upregulated in B cell chronic lymphocytic leukemia and in some centroblastic/centrocytic lymphoma cases. CD23 is used in the differentiation of small lymphocytic lymphomas and mantle cell lymphoma (2).
Related Pathway
Hematopoietic cell lineage

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD23 antibody [EPR3617(IHC)]; Anti-CD23 antibody [EPR3617] at 1/500 dilution + Human lymph node at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 36 kDa.
WB Image
Western blot - CD23 antibody [EPR3617(IHC)]; All lanes : Anti-CD23 antibody [EPR3617] at 1/500 dilution.Lane 1 : Raji lysate.Lane 2 : Lymph node lysate.Lane 3 : Human tonsil lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 36 kDa.
Assay Image
Other-Anti-CD23 antibody [EPR3617(IHC)](TA310263); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD23 antibody [EPR3617(IHC)]; TA310263, at a 1/100 dilution, staining CD23 in formalin fixed, paraffin embedded Human tonsil tissue by Immunohistochemistry. Detection: DAB staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD23 antibody [EPR3617(IHC)](TA310263); TA310263 showing positive staining in Normal tonsil tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD23 antibody [EPR3617(IHC)](TA310263); TA310263 showing negative staining in Normal heart tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD23 antibody [EPR3617(IHC)](TA310263); TA310263 showing negative staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD23 antibody [EPR3617(IHC)](TA310263); TA310263 showing negative staining in Normal brain tissue.

 

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