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Anti-CD23 Antibody EPR3617

WB(1)

IHC(1)

Gene Name Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1 Synonyms: BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF Immunogen A synthetic peptide corresponding to residues in human CD23 was used as an immunogen. Buffer Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. Clone Name EPR3617 Isotype Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IHC Suggested Dilutions WB: 1:2500 - 5000; IP: 1:50; Background CD23, a type II transmembrane glycoprotein, is a key molecule for B-cell activation and growth and functions as a receptor for IgE. It plays essential roles in the regulation of IgE production and in the differentiation of B-cells. CD21 has been identified as a ligand for CD23 in the control of IgE production. It is expressed in many hematopoietic cell types (1). CD23 expression is upregulated in B cell chronic lymphocytic leukemia and in some centroblastic/centrocytic lymphoma cases. CD23 is used in the differentiation of small lymphocytic lymphomas and mantle cell lymphoma (2). Related Pathway Hematopoietic cell lineage

Related Lysate from OriGene • Transient overexpression lysate of Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • FCER2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • FCER2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Fcer2a - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • FCER2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Fcer2a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)