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Anti-CCR7 Antibody E75


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against CCR7/CKR7
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419718) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in loop-3 extracellular domain of human C-C chemokine receptor type 7 was used as immunogen. The antibody does not cross-react with other CKR family members. Predicted to cross-react with pig and bovine based on sequence homology.
Clone NameE75 IsotypeIgG
Species ReactivityMouse, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:2000-5000; IHC 1:50-100; ICC: 1:50-100;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens chemokine (C-C motif) receptor 7 (CCR7)
Alternative NameBLR2; CD197; CDw197; CMKBR7; EBI1
Database LinkNP_001829
Entrez Gene 1236 Human
Entrez Gene 12775 Mouse
FunctionCCR7, or C-C chemokine receptor type 7, is a G protein-coupled, seven-transmembrane domain receptor protein. Originally identified as the EBV-induced gene-1 (1), CCR7 was later found to be the receptor for the chemokines CCL21 (SLC, 6Ckine, Exodus-2) (3) and CCL19 (MIP-3, Exodus-3, ELC) (4). CCR7 is expressed in lymphoid tissues and activated B and T lymphocytes (2). It is up-regulated in B cells infected with Epstein-Barr virus and T cells infected with herpesvirus 6 or 7 (4).
Related PathwayGPCRTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Anti-CCR7 antibody [E75] (TA310253) at 1/500 dilution + Daudi cell lysate


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