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Home All anti-CCNB1 antibodies

Anti-CCNB1 Phospho Antibody EPR3670

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310251
  • Rabbit Monoclonal antibody against Cyclin B1, Ps126 (CCNB1) (Phospho-specific)
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding Serine 126 of human Cyclin B1 was used as an immunogen. This antibody only detects Cyclin B1 phosphorylated at Serine 126.
Clone NameEPR3670 Isotype
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000 - 10,000; ICC: 1:50 - 100; IP: 1:20; FC: 1:50;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens cyclin B1 (CCNB1)
Alternative NameCCNB
Database LinkNP_114172
FunctionCyclin B1 regulates mitosis in conjunction with Cdc2 kinase to form the Cdc2-cyclin B1 complex also known as maturation promoting factor (MPF) (1-2). The activation of the complex begins when the regulatory subunit, cyclin B1, associates with the catalytic subunit of Cdc2. Cyclin B1 levels rise during S phase and G2, and peak at mitosis. The timing of mitosis can also be influenced by changes in cyclin B1Cdc2 localization. Cyclin B1 is mostly located in the cytoplasm during S and G2 phases and then rapidly accumulates in the nucleus at the onset of prophase (3).
Related Pathway
Cell cycle
Hedgehog signaling pathway

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WB Image
Western blot analysis on HeLa cell lysates using anti-Phospho-Cyclin B1 (pS126) RabMAb. Cells were either (A) untreated or (B) treated with Nocodazole.

 

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