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Anti-BMP4 Antibody EPR6211
Also for BMP4 (NM_001202)
|A synthetic peptide corresponding to residues in human BMP4 was used as an immunogen.|
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; FC: 1:100 - 1:500; ICC/IF: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1|
|BMP2B; BMP2B1; MCOPS6; OFC11; ZYME|
|BMP4 is a member of the bone morphogenetic protein family, which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva (1). |
Hedgehog signaling pathway
TGF Beta Signaling Pathway
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Western blot - Anti-BMP4 antibody [EPR6211]; All lanes : Anti-BMP4 antibody [EPR6211] at 1/10000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : A549 lysate.Lane 3 : HeLa lysate.Lane 4 : A431 lysate.Lane 5 : Human heart lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 47 kDa.
Other-Anti-BMP4 antibody [EPR6211](TA310213); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMP4 antibody [EPR6211]; TA310213, at 1/100, staining BMP4 in paraffin embedded Human colon tissue by Immunohistochemistry.